Leveraging Preclinical Models to Develop Therapies for NF1

Research Published from Synodos Group Developing Pig Models

The Gilbert Family Foundation Gene Therapy Initiative

Genetically Engineered Pigs May Fly as Cancer Models

‘Dream Team’ of Multidisciplinary Scientists Team up in Unique NF Research Consortium

Spontaneous and Engineered Large Animal Models of Neurofibromatosis Type 1, International Journal of Molecular Sciences, 2021.

Neurofibromatosis in the Era of Precision Medicine: Development of MEK Inhibitors and Recent Successes with Selumetinib, Evolving Therapies, 2021.

Selumetinib normalizes Ras/MAPK signaling in clinically relevant neurofibromatosis type 1 minipig tissues in vivo, Neuro-oncology Advances, 2021.

Generically engineering minipigs model the major clinical features of human neurofibromatosis type 1, Communications Biology, 2018.

Engineered Swine Models of Cancer, Frontiers in Genetics, 2016.